I'm left handed. I'm owner of Mouse 650L Left and Mouse Lift for left. Related to left-right mouse button swap option, Mouse Lift work perfect. Buttons are swapped in hardware so all is working as expected. On 650L left for some reason mouse are not swaped in hardware, so I have to use software driver option that is lacing on many places. First Because Im using Mouse Lift left and 650L left on same laptop I need to set this option when changing mouse. Other issue is that whn this option is set it is still not working while using RDP and logging on remote servers, virtual machines, etc... optimal solution will be that 650L left have buttons swapped in hardware like Mouse Lift.