Hi. I believe that my MX Keys is triggering Play/Pause on macOs from time to time when it wakes up (the keyboard). I've had similar behaviour on PC which was resolved by uninstalling logitech software (I had the logi+ beta and the previous 'official' version).
The strange thing is: the keybinding for the Play/pause button doesn't trigger macOs Play/Pause action (the same way macbook pro keyboard does), but when the issue happens it gets triggered a lot (multiple times per minute).