Logi Options+ has had a bug for a long time (years) on macOS which causes the "Scroll Direction" option to stop working in "Standard" mode after the computer goes to sleep. I've been dealing with this issue on every Mac I've owned for at least the past 5 years.

I haven't bothered reaching out in awhile about the issue because I wrote a quick UNIX shell script that fixes the issue by killing the logioptionsplus_agent which then restarts automatically and it starts working 5-10 seconds later as desired:

--

!/bin/sh

kill -9 $(ps aux | grep "MacOS/logioptionsplus_agent" | grep -v grep | awk '{print $2}')

It's happened with multiple models of mice over the years; currently I have two M535 mice, one for home office and one for laptop bag when traveling. Both are registered with my Logitech account.