Custom per app settings for the MX Master mouse need to work across Fusion 360 updates.

Autodesk aren't going to change the way they install Fusion 360, seeing as it's been like this for ages, so it's up to Logitech to fix this. Other third-party mouse controllers are able to still work with custom settings in Fusion 360 when it updates, but Options+ is not. This has gone on long enough without a fix.