My current setup is my mouse and keyboard connected to my M1 mac via bluetooth on switch 1 and on switch 2 i have the keyboard and mouse connected to my windows pc via the usb adaptor. Now if i turn on 'Use F1, F2, Etc. keys as standard function keys' on Windows it locks out the Easy-Switch buttons on the keyboard and wont allow it to change to 1 or 3. But if i disable it it does.