All my custom gestures stopped working... AGAIN! I moved to this Logi Option+ to see if this issue would stop happening (also happening with the previous software Logitech bundles).

FYI, when this happens, the mouse itself isn't recognized in the Logi Option + (also the case with the previous software). It shows as "Inactive" in the Logi Option +.
Searching, this is a very common issue for MX Master 3: https://www.reddit.com/r/LogitechG/comments/l0ft8j/mx_master_3_gesture_button_randomly_stops_working/

FIX IT Logitech! I'm looking at buying Logitech mouse and keyboard for my team (9 and growing) but this is COMPLETELY UNACCEPTABLE.