I don't know if it is due to my OS version (MacOs Monterey 12.0.1) or my Options+ version (0.60.3677) but both my MX Master 3 and my MX Keys (Full size) end up "Inactive" in the Options+ menu suddenly after working correctly for a period of time. They are both still connected and working with my Macbook Pro however as they are recognized as inactive, all my configured settings and options are unavailable. Could it be related to locking and unlocking the laptop when I leave for a while? I will check it out next time.