Quite often when I start working in the morning, after keeping the notebook sleeping, and the mouse turned off overnight, the mouse (MX master 3 for Mac) would show 'inactive' in the Option+. And the custom-defined buttons/functions do not work (Like screen navigation, screenshot) (They resort to default functions I think). Sometimes this gets somehow fixed after a few hours' use, for reason that I don't know.
System: Mac OS Big Sur 11.4
Machine: MacBook Pro (16-inch, 2019)